Acquired von willebrand's disease, IgE polyclonal gammopathy and griseofulvin therapy
نویسندگان
چکیده
منابع مشابه
Acquired von Willebrand's disease associated with gastrointestinal angiodysplasia and monoclonal gammopathy.
Sir, Acquired von WillebrandÊs Disease (AVWD) is a rare bleeding disorder, usually occurs in elderly patients. We would like to present case with recurrent gastrointestinal bleeding diagnosed to have AVWD with inhibitors. A 63 years male presented with a history of recurrent episodes of lower gastrointestinal bleeding for three years. He had also a history of occasional epistaxis and skin bleed...
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We present a case of a 79-year-old male who presented with retroperitoneal hematoma a week after motor vehicle accident. Prior history and family history of bleeding were nonsignificant. His activated partial thromboplastin time was found to be prolonged in the emergency department. Further workup with coagulation studies showed decreased factor VIII, vWF antigen, and vWF:ristocetin cofactor as...
متن کاملHigh-dose intravenous gammaglobulin therapy for acquired von Willebrand disease.
Patients with acquired von Willebrand disease may present with severe bleeding, which is usually difficult to manage. Adequate haemostasis in acquired von Willebrand disease may be achieved with the infusion of factor VIII/von Willebrand factor concentrates or with the administration of desmopressin. We report a case of acquired von Willebrand disease with severe postoperative bleeding, respond...
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Antibody responses of the immunoglobulin E (IgE) class are regulated by a finely tuned network of cellular and molecular interactions. The differentiation of IgE B lymphocytes is controlled by antigen-specific and non-antigen-specific T helper and suppressor cells and their molecular products (1-3). The antigen-specific cellular interaction can be carried out by thymus-derived (T) cells which r...
متن کاملAcquired von Willebrand disease associated with free lambda light chain monoclonal gammopathy, normal bleeding time and response to prednisone.
We report a case of acquired von Willebrand's syndrome with severe gastrointestinal bleeding and associated free monoclonal lambda light chains. The patient had a rapid sustained clinical and laboratory response to the administration of prednisone. Of note in this patient was the occurrence of angiodysplasia which has previously been reported in association with acquired von Willebrand's syndro...
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ژورنال
عنوان ژورنال: American Journal of Hematology
سال: 1992
ISSN: 0361-8609,1096-8652
DOI: 10.1002/ajh.2830410218